Gin-Den Chen Selected Research

5-Methoxytryptamine (5 Methoxytryptamine)

11/2017	Melatonin impedes Tet1-dependent mGluR5 promoter demethylation to relieve pain.
4/2016	Melatonin relieves neuropathic allodynia through spinal MT2-enhanced PP2Ac and downstream HDAC4 shuttling-dependent epigenetic modification of hmgb1 transcription.

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Gin-Den Chen Research Topics

Disease

16	Hyperalgesia 01/2021 - 02/2008
13	Pain (Aches) 08/2019 - 08/2009
6	Neuralgia (Stump Neuralgia) 01/2021 - 05/2012
6	Neoplasms (Cancer) 12/2008 - 06/2006
5	Prolapse 12/2014 - 01/2003
5	Uterine Cervical Neoplasms (Cancer of the Cervix) 12/2008 - 05/2002
3	Urinary Incontinence 09/2019 - 05/2008
3	Interstitial Cystitis (Interstitial Cystitis, Chronic) 05/2019 - 11/2012
3	Hypersensitivity (Allergy) 11/2017 - 03/2013
3	Carcinoma (Carcinomatosis) 05/2007 - 05/2002
2	Lacerations 01/2021 - 01/2019
2	Stress Urinary Incontinence 09/2019 - 06/2008
2	Wounds and Injuries (Trauma) 01/2019 - 02/2004
2	Pelvic Pain 11/2012 - 09/2008
2	Spinal Cord Injuries (Spinal Cord Injury) 09/2011 - 03/2010
2	Ataxia (Dyssynergia) 09/2011 - 03/2010
2	Referred Pain 04/2010 - 01/2010
2	Lymphatic Metastasis 12/2008 - 03/2008
2	Carcinogenesis 10/2007 - 10/2007
2	Squamous Cell Carcinoma (Epidermoid Carcinoma) 10/2007 - 10/2007
1	Hypertension (High Blood Pressure) 12/2021
1	Lower Urinary Tract Symptoms 01/2021
1	Proteinuria 10/2020
1	Leukemia 01/2020
1	Urge Urinary Incontinence (Urge Incontinence) 09/2019
1	Nocturia 05/2019
1	Alzheimer Disease (Alzheimer's Disease) 01/2019
1	Pelvic Organ Prolapse 01/2019
1	Chronic Pain 04/2016
1	Cystocele 12/2014

Drug/Important Bio-Agent (IBA)

18	Proteins (Proteins, Gene)FDA Link 10/2020 - 02/2004
5	Small Interfering RNA (siRNA)IBA 01/2021 - 05/2012
4	Freund's AdjuvantIBA 01/2018 - 12/2012
4	Phosphotransferases (Kinase)IBA 03/2013 - 06/2006
4	Messenger RNA (mRNA)IBA 03/2013 - 02/2004
3	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 03/2013 - 02/2011
3	GlucocorticoidsIBA 03/2013 - 11/2012
3	Matrix Metalloproteinase 2 (Gelatinase A)IBA 03/2008 - 10/2007
2	CreatinineIBA 12/2021 - 10/2020
2	BC-1215IBA 01/2021 - 12/2015
2	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 01/2020 - 08/2019
2	Hyaluronic Acid (Hyaluronan)IBA 05/2019 - 09/2014
2	Calcium-Calmodulin-Dependent Protein Kinase Type 2IBA 01/2018 - 02/2008
2	5-Methoxytryptamine (5 Methoxytryptamine)IBA 11/2017 - 04/2016
2	MelatoninIBA 11/2017 - 04/2016
2	MT2 Melatonin ReceptorIBA 11/2017 - 04/2016
2	Analgesics (Analgesic Drugs)IBA 04/2016 - 12/2015
2	Histone Deacetylases (Histone Deacetylase)IBA 04/2016 - 07/2015
2	AcidsIBA 03/2016 - 12/2012
2	Protein Tyrosine PhosphatasesIBA 03/2016 - 05/2012
2	AMPA Receptors (AMPA Receptor)IBA 12/2015 - 12/2012
2	Polypropylenes (Polypropylene)IBA 12/2014 - 03/2005
2	SuspensionsIBA 12/2014 - 04/2005
2	Type A Botulinum Toxins (Botox)FDA Link 09/2011 - 03/2010
2	Protein-Tyrosine Kinases (Tyrosine Kinase)IBA 02/2011 - 01/2010
2	LigandsIBA 02/2011 - 01/2010
2	src-Family KinasesIBA 02/2011 - 01/2010
2	Eph Family Receptors (Eph Receptors)IBA 02/2011 - 01/2010
2	N-Methylaspartate (NMDA)IBA 04/2010 - 08/2009
2	Estrogen Receptor betaIBA 04/2010 - 08/2009
2	Estrogen Receptor alphaIBA 04/2010 - 08/2009
2	Estrogens (Estrogen)FDA Link 08/2009 - 09/2008
2	Telomerase (Telomerase Reverse Transcriptase)IBA 12/2008 - 05/2007
2	SteroidsIBA 09/2008 - 02/2007
1	coactivator-associated arginine methyltransferase 1IBA 01/2021
1	Glucose (Dextrose)FDA LinkGeneric 10/2020
1	CholesterolIBA 10/2020
1	Triglycerides (Triacylglycerol)IBA 10/2020
1	Histones (Histone)IBA 01/2020
1	Lysine (L-Lysine)FDA Link 01/2020
1	histone H3 trimethyl Lys4IBA 01/2020
1	ErbiumIBA 09/2019
1	Proteasome Endopeptidase Complex (Proteasome)IBA 01/2018
1	UbiquitinIBA 01/2018
1	DioxygenasesIBA 11/2017
1	HMGB1 Protein (HMG1)IBA 04/2016
1	Okadaic AcidIBA 04/2016
1	4-phenyl-2-propionamidotetralineIBA 04/2016
1	Phosphoric Monoester Hydrolases (Phosphatases)IBA 04/2016
1	Leucine-Rich Repeat ProteinsIBA 12/2015
1	Neutralizing AntibodiesIBA 12/2015
1	Tumor Necrosis Factor Receptors (Tumor Necrosis Factor Receptor)IBA 12/2015
1	F-Box ProteinsIBA 12/2015
1	TNF Receptor-Associated Factor 2 (TRAF2)IBA 12/2015
1	neuroligin 1IBA 10/2015
1	SolutionsIBA 09/2014

Therapy/Procedure

7	Therapeutics 01/2021 - 08/2008
7	Ligation 01/2020 - 05/2012
3	Intravesical Administration 05/2019 - 11/2012
3	Aftercare (After-Treatment) 05/2019 - 10/2006
2	Hysterectomy 09/2012 - 05/2002
2	Suburethral Slings (Tension-Free Vaginal Tape) 06/2008 - 09/2006
1	Psychology Biofeedback (Biofeedback) 01/2021
1	Lasers (Laser) 09/2019
1	Solid-State Lasers 09/2019
1	Anesthesia 09/2019
1	Episiotomy 01/2019
1	Operative Surgical Procedures 01/2019
1	Analgesia 11/2017
1	Spinal Injections 04/2016